MetaSystems是一家雇員持股的德國(guó)公司，專門從事自動(dòng)掃描和成像系統(tǒng)的開(kāi)發(fā)，用于細(xì)胞遺傳學(xué),癌癥遺傳學(xué)、毒理學(xué)、病理學(xué)、法醫(yī)科學(xué)和其他應(yīng)用領(lǐng)域。

發(fā)展史簡(jiǎn)介

1986年 --- 由德國(guó)海德堡大學(xué)應(yīng)用物理研究所技術(shù)轉(zhuǎn)移而成立，專注于細(xì)胞遺傳學(xué)及分子遺傳學(xué)自動(dòng)化圖像工作站之研發(fā)

1987年 --- *套Metafer系列之MSearch分裂中期細(xì)胞掃描儀安裝完成

1991年 --- *套Ikaros染色體核型分析工作站安裝完成

1994年 --- 發(fā)表ISIS熒光原位雜交圖像分析工作站

1997年 --- *套Metafer系列之RCDetect罕有細(xì)胞自動(dòng)掃描儀安裝完成發(fā)表mFISH軟件

1998年 --- 發(fā)表24XCyte mFISH熒光探針及mBAND熒光探針

2000年 --- 發(fā)表Metafer系列新成員- MetaCyte間期細(xì)胞熒光點(diǎn)掃描儀

2004年 --- 成立MetaSystems Aisa公司負(fù)責(zé)亞洲地區(qū)業(yè)務(wù)推廣及技術(shù)支持

2006年 --- 在近70個(gè)國(guó)家800多個(gè)實(shí)驗(yàn)室中已安裝超過(guò)2000套工作站，成為歐州及澳州地區(qū)之。

2009/2010年 --- 投入研發(fā)自動(dòng)化虛擬幻燈片成像系統(tǒng)

在大力開(kāi)發(fā)成像系統(tǒng)的同時(shí)，Mestasystem也逐步擴(kuò)增其探針產(chǎn)品系列，如全染色體涂染試劑盒（XCP）、小鼠和大鼠多色mFISH探針（21XMouse和22XRat）、染色體臂特異性mFISH探針(XaCyte)等。早在2009年MetaSystems就曾引進(jìn)新系列用于血液學(xué)研究的染色體特殊位點(diǎn)探針。

Metasystems公司FISH 探針產(chǎn)品系列

1. XL XCyting Locus-Specific Probe Kits位點(diǎn)特異性探針

血液學(xué)/腫瘤學(xué)熒光原位雜交探針

Chronic Myeloproliferative Disorders/

慢性骨髓增生性疾病 Myelodysplastic Syndromes/

骨髓增生異常綜合癥 Burkitt Lymphoma/

伯基特淋巴瘤

CLL (Chronic Lymphocytic Leukemia)/

慢性淋巴細(xì)胞白血病 AML (Acute Myeloid Leukemia)/

急性骨髓性白血病 Diff. Large B-Cell Lymphoma/

彌漫性大B淋巴瘤

ALL (Acute Lymphocytic Leukemia)/

急性淋巴細(xì)胞性白血病 Multiple Myeloma/

多發(fā)性骨髓瘤 Follicular Lymphoma/

濾泡型淋巴瘤

Mantle Cell Lymphoma/

套細(xì)胞淋巴瘤

2. XA XCyting AneuScore Probe Kits

3. XCP XCyting Chromosome Paints

XCyting Whole Chromosome Paints/全染色體涂染探針

Human Chromosomes/人全染色體涂染探針 Mouse and Rat Chromosomes/小鼠及大鼠染色體涂染探針

XCyting 染色體臂特異性探針

4.XCE XCyting Centromere Enumeration Probes

5.XCyting Multicolor DNA Probe Kits

人類染色體多色FISH探針試劑盒

24XCyte mFISH Probe Kit Arm-Specific mFISH Probe Kit/染色體臂特異性mFISH探針 Centromeric mFISH Kit/著絲粒mFISH探針

小鼠和大鼠染色體多色FISH探針試劑盒

Metasystems D-1411-050-FI XMP 11 Mouse Chromosome 11 Painting Probe 50 µl ￥3,496.90

Metasystems D-1421-050-FI XMP Y Mouse Chromosome Y Painting Probe 50 µl ￥3,496.90

Metasystems D-1419-050-FI XMP 19 Mouse Chromosome 19 Painting Probe 50 µl ￥3,496.90

Metasystems D-1414-050-OR XMP 14 Mouse Chromosome 14 Painting Probe 50 µl ￥3,496.90

Metasystems D-1504-050-OR XRP 4 Rat Chromosome 4 Painting Probe 50 µl ￥3,496.90

Metasystems D-1406-050-OR XMP 6 Mouse Chromosome 6 Painting Probe 50 µl ￥3,496.90

Metasystems D-1402-050-FI XMP 2 Mouse Chromosome 2 Painting Probe 50 µl ￥3,496.90

Metasystems D-0224-030-DI XCyte Y, Chromosome Y mBAND probe 30 µl ￥5,142.50

Metasystems D-1403-050-OR XMP 3 Mouse Chromosome 3 Painting Probe 50 µl ￥3,496.90

Metasystems D-1405-050-FI XMP 5 Mouse Chromosome 5 Painting Probe 50 µl ￥3,496.90

Metasystems D-1401-050-OR XMP 1 Mouse Chromosome 1 Painting Probe 50 µl ￥3,496.90

Metasystems D-0224-120-DI XCyte Y, Chromosome Y mBAND probe 120 µl ￥14,399.00

Metasystems D-0905-025-TF TissueFISH Pretreatment Kit 20-30 Slides ￥5,142.50

Metasystems D-0902-500-DA DAPI/Antifade (250 ng/ml) 500 µl ￥617.10

Metasystems D-1522-050-OR XRP Y Rat Chromosome Y Painting Probe 50 µl ￥3,496.90

Metasystems D-1521-050-OR XRP X Rat Chromosome X Painting Probe 50 µl ￥3,496.90

Metasystems D-1522-050-FI XRP Y Rat Chromosome Y Painting Probe 50 µl ￥3,496.90

Metasystems D-1520-050-FI XRP 20 Rat Chromosome 20 Painting Probe 50 µl ￥3,496.90

Metasystems D-1519-050-OR XRP 19 Rat Chromosome 19 Painting Probe 50 µl ￥3,496.90

Metasystems D-1519-050-FI XRP 19 Rat Chromosome 19 Painting Probe 50 µl ￥3,496.90

Metasystems D-1520-050-OR XRP 20 Rat Chromosome 20 Painting Probe 50 µl ￥3,496.90

Metasystems D-1412-050-OR XMP 12 Mouse Chromosome 12 Painting Probe 50 µl ￥3,496.90

Metasystems D-0224-060-DI XCyte Y, Chromosome Y mBAND probe 60 µl ￥8,022.30

Metasystems D-0223-120-DI XCyte X, Chromosome X mBAND probe 120 µl ￥14,399.00

Metasystems D-0202-060-DI XCyte 2, Chromosome 2 mBAND probe 60 µl ￥8,022.30

Metasystems D-0203-030-DI XCyte 3, Chromosome 3 mBAND probe 30 µl ￥5,142.50

Metasystems D-0425-060-DI 21XMouse - Mouse Multicolor Whole Chromosome Painting mFISH Probe Kit 60 µl ￥18,513.00

Metasystems D-1100-200-OR XCP Probe Mix, Customized 10x 200 µl ￥71,995.00

Metasystems D-1100-202-MC XCP Probe Mix, Customized 3 colors 10x 200 µl ￥78,166.00

Metasystems D-0327-050-FI Kit containing 12 XCPs, Chromosomes 13-22, X, and Y 12x 50 µl ￥28,798.00

Metasystems D-0324-100-OR XCP Y, Chromosome Y Painting Probe 100 µl ￥4,525.40

Metasystems D-0323-050-OR XCP X, Chromosome X Painting Probe 50 µl ￥2,879.80

Metasystems D-0323-050-FI XCP X, Chromosome X Painting Probe 50 µl ￥2,879.80

Metasystems D-0322-100-OR XCP 22, Chromosome 22 Painting Probe 100 µl ￥4,525.40

Metasystems D-0321-050-OR XCP 21, Chromosome 21 Painting Probe 50 µl ￥2,879.80

Metasystems D-0206-120-DI XCyte 6, Chromosome 6 mBAND probe 120 µl ￥14,399.00

Metasystems D-0213-030-DI XCyte 13, Chromosome 13 mBAND probe 30 µl ￥5,142.50

Metasystems D-0219-120-DI XCyte 19, Chromosome 19 mBAND probe 120 µl ￥14,399.00

Metasystems D-0217-060-DI XCyte 17, Chromosome 17 mBAND probe 60 µl ￥8,022.30

Metasystems D-0216-060-DI XCyte 16, Chromosome 16 mBAND probe 60 µl ￥8,022.30

Metasystems D-0216-120-DI XCyte 16, Chromosome 16 mBAND probe 120 µl ￥14,399.00

Metasystems D-0215-120-DI XCyte 15, Chromosome 15 mBAND probe 120 µl ￥14,399.00

Metasystems D-0216-030-DI XCyte 16, Chromosome 16 mBAND probe 30 µl ￥5,142.50

Metasystems D-0215-030-DI XCyte 15, Chromosome 14 mBAND probe 30 µl ￥5,142.50

Metasystems D-0214-120-DI XCyte 14, Chromosome 14 mBAND probe 120 µl ￥14,399.00

Metasystems D-0214-030-DI XCyte 14, Chromosome 13 mBAND probe 30 µl ￥5,142.50

Metasystems D-0213-120-DI XCyte 13, Chromosome 13 mBAND probe 120 µl ￥14,399.00

Metasystems D-0213-060-DI XCyte 13, Chromosome 13 mBAND probe 60 µl ￥8,022.30

Metasystems D-0212-120-DI XCyte 12, Chromosome 12 mBAND probe 120 µl ￥14,399.00

Metasystems D-0212-030-DI XCyte 12, Chromosome 12 mBAND probe 30 µl ￥5,142.50

Metasystems D-0212-060-DI XCyte 12, Chromosome 12 mBAND probe 60 µl ￥8,022.30

Metasystems D-0210-120-DI XCyte 10, Chromosome 10 mBAND probe 120 µl ￥14,399.00

Metasystems D-0211-060-DI XCyte 11, Chromosome 11 mBAND probe 60 µl ￥8,022.30

Metasystems D-0211-120-DI XCyte 11, Chromosome 11 mBAND probe 120 µl ￥14,399.00

Metasystems D-0210-060-DI XCyte 10, Chromosome 10 mBAND probe 60 µl ￥8,022.30

Metasystems D-0209-060-DI XCyte 9, Chromosome 9 mBAND probe 60 µl ￥8,022.30

Metasystems D-0208-120-DI XCyte 8, Chromosome 8 mBAND probe 120 µl ￥14,399.00

Metasystems D-1525-060-DI 22XRat - Rat Multicolor Whole Chromosome Painting mFISH Probe Kit 60 µl ￥18,513.00

Metasystems D-0125-600-DI 24XCyte - Human Multicolor Whole Chromosome Painting mFISH Probe Kit 600 µl ￥123,420.00

Metasystems D-0125-120-DI 24XCyte - Human Multicolor Whole Chromosome Painting mFISH Probe Kit 120 µl ￥28,592.30

Metasystems D-0125-060-DI 24XCyte - Human Multicolor Whole Chromosome Painting mFISH Probe Kit 60 µl ￥15,324.65

Metasystems D-1100-200-MC XCP Probe Mix, Customized 5 colors 10x 200 µl ￥143,990.00

Metasystems D-1100-200-FI XCP Probe Mix, Customized 10x 200 µl ￥71,995.00

Metasystems D-0328-050-TC Kit containing 3 XCPs, 3-color - XCP Probe Mix 1-2-4 100 µl ￥8,228.00

Metasystems D-0327-050-OR Kit containing 12 XCPs, Chromosomes 13-22, X, and Y 12x 50 µl ￥28,798.00

Metasystems D-0326-050-OR Kit containing 12 XCPs, Chromosomes 1-12 12x 50 µl ￥28,798.00

Metasystems D-0326-050-FI Kit containing 12 XCPs, Chromosomes 1-12 12 X 50 µl ￥28,798.00

Metasystems D-0325-050-OR Kit containing 24 XCPs, Chromosomes 1-22, X, and Y 24x 50 µl ￥53,482.00

Metasystems D-0325-050-FI Kit containing 24 XCPs, Chromosomes 1-22, X, and Y 24x 50 µl ￥53,482.00

Metasystems D-0324-050-OR XCP Y, Chromosome Y Painting Probe 50 µl ￥2,879.80

Metasystems D-0324-050-FI XCP Y, Chromosome Y Painting Probe 50 µl ￥2,879.80

Metasystems D-0324-100-FI XCP Y, Chromosome Y Painting Probe 100 µl ￥4,525.40

Metasystems D-0323-100-OR XCP X, Chromosome X Painting Probe 100 µl ￥4,525.40

Metasystems D-0323-100-FI XCP X, Chromosome X Painting Probe 100 µl ￥4,525.40

Metasystems D-0322-050-OR XCP 22, Chromosome 22 Painting Probe 50 µl ￥2,879.80

Metasystems D-0322-050-FI XCP 22, Chromosome 22 Painting Probe 50 µl ￥2,879.80

Metasystems D-0319-050-FI XCP 19, Chromosome 19 Painting Probe 50 µl ￥2,879.80

Metasystems D-0319-100-FI XCP 19, Chromosome 19 Painting Probe 100 µl ￥4,525.40

Metasystems D-0319-050-OR XCP 19, Chromosome 19 Painting Probe 50 µl ￥2,879.80

Metasystems D-0319-100-OR XCP 19, Chromosome 19 Painting Probe 100 µl ￥4,525.40

Metasystems D-0316-100-OR XCP 16, Chromosome 16 Painting Probe 100 µl ￥4,525.40

Metasystems D-0317-050-FI XCP 17, Chromosome 17 Painting Probe 50 µl ￥2,879.80

Metasystems D-0317-100-FI XCP 17, Chromosome 17 Painting Probe 100 µl ￥4,525.40

Metasystems D-0317-100-OR XCP 17, Chromosome 17 Painting Probe 100 µl ￥4,525.40

Metasystems D-0318-050-FI XCP 18, Chromosome 18 Painting Probe 50 µl ￥2,879.80

Metasystems D-0317-050-OR XCP 17, Chromosome 17 Painting Probe 50 µl ￥2,879.80

Metasystems D-0316-050-OR XCP 16, Chromosome 16 Painting Probe 50 µl ￥2,879.80

Metasystems D-0316-050-FI XCP 16, Chromosome 16 Painting Probe 50 µl ￥2,879.80

Metasystems D-0316-100-FI XCP 16, Chromosome 16 Painting Probe 100 µl ￥4,525.40

Metasystems D-0315-100-OR XCP 15, Chromosome 15 Painting Probe 100 µl ￥4,525.40

Metasystems D-0315-100-FI XCP 15, Chromosome 15 Painting Probe 100 µl ￥4,525.40

Metasystems D-0315-050-FI XCP 15, Chromosome 15 Painting Probe 50 µl ￥2,879.80

Metasystems D-0825-050-OG XCE X/Y, CenX/Y 50 µl ￥2,468.40

Metasystems D-0825-200-OG XCE X/Y, CenX/Y 4x 50 µl ￥8,228.00

Metasystems D-0826-050-OG XCE 7/8, Cen7/8 50 µl ￥2,468.40